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Saccades in presymptomatic and early stages of Huntington disease - PubMed » Abnormalities in eye movement measures are a sensitive biomarker in the prediagnostic and early stages of Huntington disease (HD). These measures may be more sensitive to prediagnostic changes in HD than the currently employed neurologic motor assessment. Pubmed.ncbi.nlm.nih.gov

Complex I defect in muscle from patients with Huntington's disease - PubMed » We found a variable defect of complex I of the mitochondrial respiratory chain, ranging in severity from 25% to 63% of control values, in muscle of patients with Huntington's disease (HD). The most severe defect was observed in the patient with the greatest expansion of CAG triplets. Muscle morpholo … Pubmed.ncbi.nlm.nih.gov

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